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+ | Link to [[:wikitox:problems_for_discussion_2_vasodilators|Problems for Discussion]] | ||
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+ | ---- | ||
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+ | ====== Vasodilators ====== | ||
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+ | This diverse group of drugs can be divided into the following groups: | ||
+ | |||
+ | - Direct acting vasodilators | ||
+ | * Nitrates: Glyceryl trinitrate, Isosorbide Mononitrate, Isosorbide Dinitrate | ||
+ | * Nitroprusside | ||
+ | * Hydralazine | ||
+ | * Diazoxide | ||
+ | * Minoxidil | ||
+ | - Alpha Antagonists | ||
+ | * Centrally acting: Clonidine (discussed separately), Methyl dopa | ||
+ | * Peripheral Non-selective: Phentolamine, Phenoxybenzamine | ||
+ | * Peripheral Selective: Prazosin, Terazosin | ||
+ | - Angiotensin acting | ||
+ | * [[:wikitox:2.1.6.2.1.1_angiotensin_converting_enzyme_inhibitors|Angiotensin Converting Enzyme Inhibitors]] | ||
+ | * Angiotensin II Receptor Inhibitors: Candesartan, Eprosartan, Irbesartan, Losartan, Telmisartan | ||
+ | - [[:wikitox:2.1.6.1.1_calcium_channel_blockers|Calcium Channel Blockers]] (discussed separately) | ||
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+ | ===== FURTHER READING ===== | ||
+ | |||
+ | MacMillan AR, Warshawski FJ, Steinberg RA. Minoxidil overdose. Chest 1993;103(4):1290-1 [[http://www.ncbi.nlm.nih.gov/pubmed/8131492|PMID 8131492]] | ||
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+ | Jahangiri M, Holdright DR. Myocardial infarction secondary to dipyridamole overdose. //Arch Emerg Med// 1992 Mar;9(1):62-4 [[http://www.ncbi.nlm.nih.gov/pubmed/1567532|PMID 1567532]] | ||
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+ | Pigeon G, Genest J. Prolonged hydralazine hydrochloride administration in 132 hypertensive patients–Study of toxicity. //Can Med Assoc J// 1960 Oct 1;83:743-6 [[http://www.ncbi.nlm.nih.gov/pubmed/13735669|PMID 13735669]] | ||
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+ | Varon J, Duncan SR. Naloxone reversal of hypotension due to captopril overdose. //Ann Emerg Med// 1991;20(10):1125-7 [[https://www.ncbi.nlm.nih.gov/pubmed/1928887|PMID 1928887]] | ||
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+ | Farrell SE, Epstein SK. Overdose of rogaine extra strength for men topical minoxidil preparation. //J Toxicol Clin Toxicol// 1999;37(6):781-783 [[https://www.ncbi.nlm.nih.gov/pubmed/10584592|PMID 10584592]] | ||
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+ | Rygnestad TK, Dale O. Self-poisoning with prazosin. //Acta Med Scand// 1983;213(2):157-8 [[https://www.ncbi.nlm.nih.gov/pubmed/6837333|PMID 6837333]] | ||
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+ | Arora R, Timoney M, Melelli L. Acute Myocardial infarction after the use of sildenafil. //N Eng J Med// 1999;341(9):700 [[https://www.ncbi.nlm.nih.gov/pubmed/10475830|PMID 10475830]] | ||
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