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wikitox:3.2.1.1.2_differential_diagnosis_of_anticholinergic_toxidrome [2018/09/01 09:00] (current)
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 +====== Differential Diagnosis of Anticholinergic Toxidrome ======
 +
 +There are a number of frequently taken drugs that commonly cause the [[:​wikitox:​3.2.1.3_toxidromes|anticholinergic syndrome]].
 +
 +The most common (in Australia) are:
 +
 +  * [[:​wikitox:​2.1.11.4.2_antihistamines|Antihistamines]]
 +  * [[:​wikitox:​2.1.11.4.1_anticholinergics|Anticholinergic drugs]] including
 +      * atropine
 +      * benztropine
 +      * benzhexol (trihexyphenidyl)
 +      * procyclidine
 +      * orphenadrine
 +  * [[:​wikitox:​2.1.11.9.2.1_tricyclic_antidepressants|Tricyclic antidepressants]] (TCAs)
 +  * [[:​wikitox:​2.1.11.9.3_antipsychotics|Neuroleptics]] (in particular thioridazine and chlorpromazine)
 +  * [[:​wikitox:​3.4.2.3_carbamazepine|Carbamazepine]]
 +  *  [[:​wikitox:​2.3.4.6_neurotoxic_plants|Anticholinergic plants]]
 +      * //Datura (Brugmansia) stramonium// ​ (Angel'​s trumpet)
 +      * //Atropa belladonna// ​ (Deadly Nightshade)
 +Features that help to differentiate between these drugs are:
 +
 +  * [[:​wikitox:​level_of_consciousness|LEVEL OF CONSCIOUSNESS]]
 +  * [[:​wikitox:​pupil_size_and_reaction|PUPIL SIZE and REACTION]]
 +  * [[:​wikitox:​myoclonic_jerking_or_hyperreflexia|MYOCLONIC JERKING, SEIZURES or HYPERREFLEXIA]]
 +  * [[:​wikitox:​nystagmus|NYSTAGMUS]]
 +  * [[:​wikitox:​heart_rates|HEART RATE]]
 +  * [[:​wikitox:​bowel_sounds|BOWEL SOUNDS]]
 +  * [[:​wikitox:​ecg_changes|ECG CHANGES]]
 +  * [[:​wikitox:​3.3.1.1.1_physostigmine|RESPONSE TO ANTAGONISTS]]
 +  * [[:​wikitox:​blood_concentrations|BLOOD CONCENTRATIONS]]
 +
  
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