A number of toxins lead to failure of multiple organs (commonly renal, hepatic, respiratory, cardiac, haematological and neurological).

• Colchicine
• A number of plants/mushrooms
• Paraquat
• Organochlorines
• Heavy metals
  • Iron
  • Mercury
  • Arsenic
  • Thallium
• Paracetamol
• Carbon monoxide

It is important to diagnose poisoning with metals as they have different requirements for decontamination and chelation therapy may be indicated.

• Oral and oesophageal erosions
• Major organ involved
• Blood & urine concentrations