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wikitox:3.2.1.1.7_multiorgan_failure [2018/09/01 09:00] (current)
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 +====== Multiorgan Failure ======
 +
 +A number of toxins lead to failure of multiple organs (commonly renal, hepatic, respiratory,​ cardiac, haematological and neurological).
 +
 +==== These are thankfully rare but include: ====
 +
 +  * [[:​wikitox:​2.1.1.5.1_colchicine|Colchicine]]
 +  * A number of [[:​wikitox:​2.3.4_plants|plants/​mushrooms]]
 +  * [[:​wikitox:​2.2.7.3.1_paraquat|Paraquat]]
 +  * [[:​wikitox:​2.2.7.4.4_organochlorines|Organochlorines]]
 +  * Heavy metals
 +      * [[:​wikitox:​2.1.9.6_iron|Iron]]
 +      * Mercury
 +      * [[:​wikitox:​2.2.6.1_arsenic|Arsenic]]
 +      * Thallium
 +  * [[:​wikitox:​2.1.1.1_acetaminophen|Paracetamol]]
 +  * [[:​wikitox:​2.2.9.1.1_carbon_monoxide|Carbon monoxide]]
 +
 +It is important to diagnose poisoning with metals as they have different requirements for decontamination and chelation therapy may be indicated.
 +
 +==== Features that help to differentiate between these drugs are: ====
 +
 +  * [[:​wikitox:​oesophageal_burns|Oral and oesophageal erosions]]
 +  * [[:​wikitox:​major_organ_involved|Major organ involved]]
 +  * [[:​wikitox:​blood_concentrations|Blood & urine concentrations]]
 +
  
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