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wikitox:3.3_pharmacological_basis_of_antidote_use [2018/09/01 09:00] (current)
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 +====== 3.3 Pharmacological Basis of Antidote Use ======
 +
 +Talk by Vincent Danel EAPCCT Seville on prehospital antidote:\\
 +[[http://​curriculum.toxicology.wikispaces.net/​space/​showimage/​antidotes_danel_seville.ppt|Antidotes Danel Seville.ppt [1.8 MB]]]
 +
 +  * **3.3.1 Antagonize Effects of Poison**
 +      * 3.3.1.1 Enzyme Inhibitors (eg, [[:​wikitox:​3.3.1.1.1_physostigmine|physostigmine]])
 +      * 3.3.1.2 Enzyme Reactivators (eg, pralidoxime)
 +      * 3.3.1.3 Physiological Antagonists (eg, calcium, [[:​wikitox:​3.3.1.3.2_glucagon|glucagon]])
 +      * 3.3.1.4 Receptor Antagonists (eg, atropine, flumazenil, naloxone)
 +      * 3.3.1.5 Reducing Agent (eg, methylene blue, N-acetylcysteine)
 +
 +  * **3.3.2 Dispositional Agents**
 +      * 3.3.2.1 Alcohol Dehydrogenase Antagonists
 +      * 3.3.2.2 Antivenoms/​Antibodies
 +      * 3.3.2.3 Chelators
 +      * 3.3.2.4 Cyanide Antidotes
 +      * 3.3.2.5 Enzyme/​Cofactor Replacement (eg, folinic acid, pyridoxine)
 +      * 3.3.2.6 Oxygen/​Hyperbaric Oxygen
 +
 +  * **3.3.3 Other Antidotes**
 +
  
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