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concept_blood_gas_analysis [2025/05/13 06:27] – [3. Other Useful Information on a Blood Gas] jkohts | concept_blood_gas_analysis [2025/05/13 06:36] (current) – [1.4 Is there any compensation?] jkohts | ||
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Both the lungs and kidneys adapt to compensate for acid-base disturbances in an attempt to bring the pH closer to normal. The adequacy of this compensation should be assessed. | Both the lungs and kidneys adapt to compensate for acid-base disturbances in an attempt to bring the pH closer to normal. The adequacy of this compensation should be assessed. | ||
- | **Respiratory | + | === Respiratory |
A quick rule is that the PCO₂ should roughly equal the last two digits of the pH value. This only works within a pH range of 7.1-7.6. | A quick rule is that the PCO₂ should roughly equal the last two digits of the pH value. This only works within a pH range of 7.1-7.6. | ||
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* In metabolic alkalosis, expected PCO₂ = 0.7 [HCO₃⁻] + 20 | * In metabolic alkalosis, expected PCO₂ = 0.7 [HCO₃⁻] + 20 | ||
- | **Metabolic | + | |
+ | === Metabolic | ||
Renal metabolic compensation occurs quickly via intracellular buffering, and more slowly via the kidney, where under normal conditions, HCO₃⁻ is absorbed and H⁺ is secreted in varying amounts. | Renal metabolic compensation occurs quickly via intracellular buffering, and more slowly via the kidney, where under normal conditions, HCO₃⁻ is absorbed and H⁺ is secreted in varying amounts. | ||