Differences
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| wikitox:2.1.11.4.8.2_theophylline [2025/05/13 00:07] – [Elimination] kharris | wikitox:2.1.11.4.8.2_theophylline [2025/05/13 00:08] (current) – [RISK ASSESSMENT] kharris | ||
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| ===== RISK ASSESSMENT ===== | ===== RISK ASSESSMENT ===== | ||
| - | Theophylline has a narrow therapeutic range, and signs of toxicity can develop with any supratherapeutic ingestion (>10mg/kg). | + | Theophylline has a narrow therapeutic range, and signs of toxicity can develop with any supratherapeutic ingestion (>10 mg/kg). |
| - | Ingestions of >30mg/kg are expected to cause more significant signs of toxicity and those >50mg/kg are associated with severe life-threatening toxicity. | + | Ingestions of >30 mg/kg are expected to cause more significant signs of toxicity and those > 50mg/kg are associated with severe life-threatening toxicity. |
| Children can develop toxicity from small accidental ingestions with a single 200mg modified-release tablet potentially leading to toxicity in a 10kg child. | Children can develop toxicity from small accidental ingestions with a single 200mg modified-release tablet potentially leading to toxicity in a 10kg child. | ||